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Phase II processes then need to come along and remove that toxic metabolite by conjugating it with another molecule that will facilitate its elimination

doi: 10.3945/ajcn.114.086918 Summary Keywords nutritional interventions, osteoarthritis, metabolism, inflammation, oxidative stress, gut-joint axis Citation Wang Y, Cao Z, Gao Y, Shao P, Gao S, Dong M, Tian Z, Feng Y, Xu J and Xiang C (2025) Nutritional interventions for osteoarthritis: targeting the metabolism-inflammation-oxidative stress axisclinical evidence and translational practice

It works by increasing the production of insulin and suppressing appetite, leading to significant weight loss in participants who took the medication